How to dilute 200 mcg of Misoprostol in 200ml water

Misoprostol tablets can dissolved in water by simply adding them to a known quantity of water. The concentration should however be carefully calculated. A detailed description of the process is shown below. An alternative method from South Africa is also available here.



  • Measuring jug
  • Spoon
  • Clean drinking water (200ml)
  • 1 Misoprostol tablet (200 micrograms)
  • Clean bottle

Directions on how to dilute Misoprostol in 6 easy steps:

measuring jug misoprostol

STEP ONE: Measure out 200ml of clean water using the measuring jug. A suitable container that holds exactly 200ml may be used as an alternative.
crushing a misoprostol tablet solution

STEP TWO: Crush the Misoprostol tablet with a spoon
add Misoprostol powder into water

STEP THREE: Pour the powdered Misoprostol into the water.
Stirring the misoprostol solution

STEP FOUR: Stir well with a spoon until dissolved.
Pour misoprostol solution into clean empty bottle

STEP FIVE: Pour the solution into a clean empty bottle. Please shake well before each administration.

STEP SIX: If you wish to keep the solution for later use, you will need to create a label (see example text below) with the following information and attach it to the bottle:

Example of label content below


  • 200 micrograms in 200ml (1 microgram per ml)
  • Date the solution was made up
  • Discard after 24hours
  • Amount per administration
  • For oral use only
  • Shake well before use
  • (Keep out of reach of children)