Misoprostol tablets can dissolved in water by simply adding them to a known quantity of water. The concentration should however be carefully calculated. A detailed description of the process is shown below. An alternative method from South Africa is also available here.
Equipment:
- Measuring jug
- Spoon
- Clean drinking water (200ml)
- 1 Misoprostol tablet (200 micrograms)
- Clean bottle
Directions on how to dilute Misoprostol in 6 easy steps:

STEP ONE: Measure out 200ml of clean water using the measuring jug. A suitable container that holds exactly 200ml may be used as an alternative.

STEP TWO: Crush the Misoprostol tablet with a spoon

STEP THREE: Pour the powdered Misoprostol into the water.

STEP FOUR: Stir well with a spoon until dissolved.

STEP FIVE: Pour the solution into a clean empty bottle. Please shake well before each administration.

STEP SIX: If you wish to keep the solution for later use, you will need to create a label (see example text below) with the following information and attach it to the bottle:
Example of label content below
MISOPROSTOL
- 200 micrograms in 200ml (1 microgram per ml)
- Date the solution was made up
- Discard after 24hours
- Amount per administration
- For oral use only
- Shake well before use
- PATIENTS NAME
- (Keep out of reach of children)